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Difluorocarboxyfluorescein Cadaverine, 5-isomer (FP-1227)

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Description

Difluorocarboxyfluorescein Cadaverine, 5-isomer (sold under Oregon Green™ 488 Cadaverine, 5-isomer name) is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be employed as a polar tracer and as a reactive dye for labeling proteins via a carboxylic acid moiety.

Difluorocarboxyfluorescein Cadaverineis a fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.

Difluorocarboxyfluorescein Cadaverine, 5-isomer structurally is identical to Invitrogen’s Oregon Green™ 488 Cadaverine, 5-isomer

Specifications

Unit Size5 mg, 25 mg, 100 mg
ReactivityAldehyde, carboxylic acid, ketone
Abs/Em Maxima494/517 nm
Extinction coefficient73,000 cm-1M-1
SolubilityDMSO, DMF, MeOH
Spectrally similar dyesAlexa Fluor® 488, DyLight® 488, Fluorescein, Oregon Green 488
Molecular weight496.46
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Abs/Em Spectra

Mb Mb

Applicable patents and legal notices are available at legal notices.

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