An azido-containing building block that can be used to derivatize primary amines with an azido group via a stable amide bond. The NHS ester reacts with primary amines at pH 7-9 forming a stable amide bond. The azide (N3) group reacts with terminal alkynes via CuAAC, strained cyclooctynes (e.g. DBCO or BCN compounds) via Cu-free click reaction or with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.
Unit Size | 100 mg , 1 g, 5 g |
---|---|
Molecular weight | 254.24 |
Chemical composition | C10H14N4O4 |
CAS | 866363-70-4 |
Solubility | DMSO, DMF, THF, DCM, Chloroform |
Purity | >95% (HPLC) |
Appearance | Slightly yellow oil |
Storage Conditions | -20°C. Desiccate |
Shipping Conditions | Ambient temperature |
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