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6-Azidohexanoic Acid NHS Ester (CCT-1402)



An azido-containing building block that can be used to derivatize primary amines with an azido group via a stable amide bond. The NHS ester reacts with primary amines at pH 7-9 forming a stable amide bond. The azide (N3) group reacts with terminal alkynes via CuAAC, strained cyclooctynes (e.g. DBCO or BCN compounds) via Cu-free click reaction or with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.


Unit Size100 mg , 1 g, 5 g
Molecular weight254.24
Chemical compositionC10H14N4O4
SolubilityDMSO, DMF, THF, DCM, Chloroform
Purity>95% (HPLC)
AppearanceSlightly yellow oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

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