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t-boc-N-amido-dPEG®₂₃-amine (QBD-10093)

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Description

t-boc-N-amido-dPEG®23-amine, product number QBD-10093, is a monoprotected, homobifunctional, discrete PEG (dPEG®) crosslinker. The amine groups react with carboxylic acids, active esters (e.g., NHS, TFP, PFP) of carboxylic acids, aldehydes, and ketones. The tert-butyl carbamate (t-boc) protecting group is removed quickly and easily under mild conditions. The dPEG® linker provides flexibility and water solubility to conjugate molecules. Examples of uses for this product include graphene quantum dot engineering, antibody and enzyme immobilization, development of biomolecular sensors, and construction of supramolecular assemblies.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1173.42; single compund
Chemical formula C₅₃H₁₀₈N₂O₂₅
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 72 atoms and 86.8 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

References

  1. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Applicable patents and legal notices are available at legal notices.

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