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CBZ-N-amido-dPEG®₃-amine (QBD-10269)



CBZ-N-amido-dPEG®₃-amine, product number QBD-10269 is a monoprotected, homobifunctional, carbonyl-reactive crosslinker. It is useful for joining two aldehydes, carboxylic acids, or active esters across a short, discrete PEG linker. The CBZ protecting group can be removed easily using hydrogen and palladium. Care should be taken to prevent or minimize exposure to air because the free amine oxidizes readily.


Unit Size1000 mg
Molecular Weight354.44; single compound
Chemical formulaC₁₈H₃₀N₂O₅
Purity> 98%
SpacersdPEG® Spacer is 15 atoms and 16.9 Å
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.


Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Applicable patents and legal notices are available at legal notices.

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