Lectins are sugar-binding proteins found in plants, viruses, microorganisms, and animals. They bind glycoconjugates in much the same way as antibodies bind antigens. As a result, researchers use lectins to explore a myriad of biological structures and processes.
Lectins bind specific carbohydrate structures, so you can use them in glycobiology to:
Some lectins can induce mitosis, so you can use them to investigate the process of lymphocyte blastogenesis and the biochemical and structural alterations associated with mitogenesis. These important applications include lymphokine production and viral coat protein (eg gp120) isolation.
At Vector Laboratories, we employ crystallization, precipitation, and chromatographic procedures as well as affinity chromatography to purify our lectins. We monitor the purification process carefully and assess the final product through:
We do this to ensure you have the best lectins available on the market.
A selection of Vector Laboratories’ lectin products is validated by the National Center for Functional Glycomics (NCFG) using the Consortium for Functional Glycomics (CFG) glycan arrays. The NCFG analyzes the glycan specificity of each lectin lot and makes the data available to the public on the NCFG website.