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TCO-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media. TCO-NHS ester is supplied as a single equatorial (major, rel-(1S-2S-5E-pR), ref 1 and 4) diastereomer. Specially formulated crystalline provides easy handling and extended shelf life.
Important Product Information:
TCO-NHS Ester is not recommended for labeling of proteins in aqueous buffers due to poor level of activation of labeled proteins (Rahim, M.K., et al., Bioconjugate Chem. 2015, 26, 352-360). TCO-PEG4-NHS Ester is well suited for protein and antibody labeling in aqueous buffers.
| Unit Size | 25 mg, 100 mg, 1000 mg |
|---|---|
| Molecular weight | 267.28 |
| Chemical composition | C13H17NO5 |
| CAS | 1191901-33-3 |
| Solubility | DMSO, DMF, DCM, THF, Chloroform |
| Purity | >95% (HPLC) |
| Appearance | White to slightly grey crystalline |
| Storage Conditions | -20°C. Desiccate |
| Shipping Conditions | Ambient temperature |
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