Sulfo TCO-Maleimide (CCT-1355)


Sulfo TCO-Maleimide a water-soluble reagent that enables simple and efficient incorporation of TCO moiety onto cysteine-containing peptides or other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. The hydrophilic sulfonated spacer arm greatly improves water solubility of TCO derivatized molecules, in many cases making it completely soluble in aqueous media. A short spacer arm adds minimal mass to modified molecules


Unit Size10 mg, 25 mg, 100 mg
Molecular weight457.50
Chemical compositionC17H27N3O8S
SolubilityDMSO, DMF, Water
Purity>95% (HPLC)
AppearanceOff-white amorphous solid to semi-solid or oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

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