TCO-PEG4-NHS Ester

TCO-PEG4-NHS Ester is a pegylated lebeling reagent with enhanced solubility in aqueous buffers used for TCO labeling of antibodies, proteins and other primary amine-containing macromolecules. A long, hydrophilic PEG4 spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.

Price range: $175.00 through $718.00

Category: TCO Reagents

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SKU: CCT-A137

CAS Number 1621096-79-4
Molecular Weight 514.57
Appearance Colorless to slightly yellow oil
Chemical Formula C24H38N2O10
Purity >95% (HPLC)
Unit Size 4x2mg, 10mg, 25mg, 100mg
Solubility DMSO, DMF, THF, Acetonitrile, Dichloromethane
Storage Instructions -20°C. Desiccate
Shipping Conditions Dry ice
Shipping Instructions Dry ice

Selected References

Ingham, E. S., et al. (2020). Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun, 11, 2102. [Nature Communications]
Sun, N., et al. (2020). Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring. Nat Commun., 11, 4489. [PubMed]
Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. , 29(6), 2028-38. [PubMed]