Alkyne-PEG4-Amine

Alkyne-PEG4-Amine is a polyethylene glycol-containing reagent with terminal primary amines (–NH2) that can be reacted with carbonyl groups in the presence of activators (e.g. EDC, or DCC) or with activated esters (e.g. NHS esters) forming a stable amide bond. The terminal alkyne group reacts with azides by a mechanism known as the Cu-catalyzed click reaction enabling efficient and specific conjugation of derivatized molecules in biological samples.