N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz)

The unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Price range: $149.00 through $691.00

Category: Glycosylation

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SKU: CCT-1084

CAS Number 361154-30-5
Molecular Weight 430.37
Appearance Slightly grey amorphous solid
Chemical Formula C16H22N4O10
Purity >90%
Unit Size 5 mg, 25 mg, 100 mg
Solubility DMSO, DMF, DCM, THF, Chloroform
Storage Instructions -20°C.
Shipping Conditions Ambient temperature
Shipping Instructions Ambient temperature

Selected References

Ranzinger, R., et al. (2020). Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. ACS Chem. Biol., 15, 10, 2692-2701. [ACSPublications]
Loebel, C., et al. (2020). Metabolic Labeling to Probe the Spatiotemporal Accumulation of Matrix at the Chondrocyte–Hydrogel Interface. Adv. Funct. Mater. [PubMed]
Song, S., et al. (2020). In Situ One-Step Fluorescence Labeling Strategy of Exosomes via Bioorthogonal Click Chemistry for Real-Time Exosome Tracking In Vitro and In Vivo. Bioconjugate Chem., 31(5), 1562-74. [PubMed]
Kim, S. H., et al. (2014). Cell labeling and tracking method without distorted signals by phagocytosis of macrophages . Theranostics, 4 (4), 420-31. [PubMed]