DBCO-Sulfo-NHS Ester (CCT-A124)

Description

DBCO-Sulfo-NHS Ester is water-soluble reagent that enables simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with DBCO moiety in 100% aqueous buffers. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds.

Specifications

Unit Size10mg, 25mg, 100mg, 500mg
Molecular weight532.50
Chemical compositionC25H21N2NaO8S
CAS1400191-52-7
SolubilityWater, DMSO, DMF
Purity>95% (HPLC)
AppearanceWhite to slightly grey crystalline
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Protein Labeling Calculator

[protein-labeling-calculator]

Selected References

  1. Wiener, J., et al. (2020). Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics. Sci Rep.10 (1), 1457. [PubMed]

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