Methyltetrazine Amine (CCT-1011)


A building block used for derivatization of carboxylic acids or activated esters with methytetrazine moiety. The stability of Methyltetrazine Amine is substantially improved compared to hydrogen substituted tetrazine-tmine. Superior stability of methyltetrazine-amine allows this reagent to be used in wider range of chemical transformations. Long-term storage of methyltetrazine-amine, especially in aqueous buffer, is also greatly improved compared to Tetrazine Amine. This reagent is supplied as HCl salt for improved stability and handling.


Unit Size25 mg, 100 mg, 500 mg, 1000 mg
Molecular weight201.23
Chemical composition
SolubilityMeOH, DMSO, DMF
Purity>95% (HPLC)
AppearancePink solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Selected References

  1. Baskin, J. M., et al. (2019). A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity. Proc Natl Acad Sci U S A116 (31), 15453-15462. [PubMed]

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