Azidoacetic Acid NHS Ester (CCT-1070)


An azido-containing building block that can be used to derivatize primary amines with an azido group via a stable amide bond. The NHS ester reacts with primary amines at pH 7-9 forming a stable amide bond. The azide (N3) group reacts with terminal alkynes via CuAAC, strained cyclooctynes (e.g. DBCO or BCN compounds) via Cu-free click reaction or with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.


Unit Size100 mg, 1000 mg, 5 g
Molecular weight198.14
Chemical compositionC6H6N4O4
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (HPLC)
AppearanceWhite crystalline
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

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