AZDye™ 488 Cadaverine is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be employed as a polar tracer and as a reactive dye for labeling proteins via a carboxylic acid moiety.
AZDye™ 488 is a water-soluble, bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. Its green fluorescence is pH independent from pH 4 to pH 10. AZDye™ 488 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates which are often used for generation of stable signals in imaging and flow cytometry.
AZDye™ 488 Cadaverine is structurally identical to Alexa Fluor® 488 Cadaverine. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine 110 core, including CF®488 Dye, DyLight® 488 and Alexa Fluor® 488.
|Unit Size||1 mg, 5 mg, 25 mg, 100 mg|
|Reactivity||Aldehydes, carboxylic acid, ketones|
|Abs/Em Maxima||494/517 nm|
|Extinction coefficient||73,000 cm-1M-1|
|Solubility||Water, DMSO, DMF|
|Spectrally similar dyes||Alexa Fluor® 488, DyLight® 488, Fluorescein, Oregon Green 488|
|Molecular weight||618.63 (protonated)|
|Shipping Conditions||Ambient temperature|
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