Accelerating Ligands
Copper(I)-catalyzed Azide-Alkyne Click Chemistry (CuAAC) relies on the presence of Copper(I) ions (Cu⁺). These ions are prone to oxidation which decreases the amount of active Cu⁺ available for reactions and leads to the formation of harmful byproducts which increase cytotoxicity in living cells.
Ligands with tertiary amine and triazine groups stabilize Cu⁺ by protecting it from degradation thus boosting the efficiency of CuAAC reactions. In addition, the reduced toxicity improves compatibility with biological systems.
Vector offers a comprehensive portfolio of CuAAC accelerating ligands providing options to meet the unique needs of your azide-alkyne cycloaddition reactions: THPTA, BTTAA, BTTES, BTTP, and TBTA.
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Price range: $69.00 through $1,812.00
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Price range: $166.00 through $1,340.00
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