Difluorocarboxyfluorescein Cadaverine, 5-isomer (sold under Oregon Green™ 488 Cadaverine, 5-isomer name) is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be employed as a polar tracer and as a reactive dye for labeling proteins via a carboxylic acid moiety.
Difluorocarboxyfluorescein Cadaverineis a fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.
Difluorocarboxyfluorescein Cadaverine, 5-isomer structurally is identical to Invitrogen’s Oregon Green™ 488 Cadaverine, 5-isomer
|Unit Size||5 mg, 25 mg, 100 mg|
|Reactivity||Aldehyde, carboxylic acid, ketone|
|Abs/Em Maxima||494/517 nm|
|Extinction coefficient||73,000 cm-1M-1|
|Solubility||DMSO, DMF, MeOH|
|Spectrally similar dyes||Alexa Fluor® 488, DyLight® 488, Fluorescein, Oregon Green 488|
|Shipping Conditions||Ambient temperature|
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