DBCO-mPEG, 5 kDa (CCT-A118)


DBCO-activated PEGylation reagents react with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. In application where the presence of copper is a concern DBCO-activated PEGylation reagents is an ideal alternative to copper requiring fluorescent alkynes.


Unit Size25mg, 100 mg, 1000 mg
Molecular weight5 kDa
SolubilityWater, DMSO, DMF, chloroform
AppearanceWhite crystalline
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Selected References

  1. Hunt, J. P., et al. (2022). Assessing site-specific PEGylation of TEM-1 β-lactamase with cell-free protein synthesis and coarse-grained simulation. J Biotechnol.345:55-63, Epub. [PubMed]
  2. Wilding, K. M., et al. (2018). The Locational Impact of Site-Specific PEGylation: Streamlined Screening with Cell-Free Protein Expression and Coarse-Grain Simulation. ACS Synth Biol.7 (2), 510-521. [PubMed]

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