CAS Number N/A | |
Molecular Weight 996.974; single compound | |
Chemical Formula C₄₇H₇₀BrN₃O₁₅ | |
Purity > 98% | |
Unit Size 25 mg, 100 mg, 500 mg | |
Solubility Methylene Chloride, Methanol, Acetonitrile, DMF, DMAC, or DMSO. | |
Spacers dPEG® Spacer is 40 atoms and 46.1 Å | |
Storage Instructions -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure. | |
Shipping Instructions Ambient |
Bromoacetamido-dPEG®₁₂-amido-DBCO
Bromoacetamido-dPEG®12-amido-DBCO, product number QBD-11223, combines a thiol-reactive bromoacetyl group with dibenzylcyclooctyne (DBCO, also known as DIBAC), a copper-free click chemistry reactive group. The two reactive groups link via a medium-length (40 atoms, 46.1 Å), flexible, single molecular weight, discrete polyethylene glycol (dPEG®) linker. The bromoacetyl group reacts chemoselectively with thiols at pH ≥ 8.0. This differs from the maleimide group, which reacts chemoselectively with sulfhydryls within the range of pH 6.5 – 7.5. The DBCO moiety is a strained cyclooctyne ring flanked by two benzyl rings on either side. DBCO was designed for strain promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry.
Price range: $230.00 through $2,076.00
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