Heterobifunctional Amine & Thiol Reactive

Cross-Linkers and DSPE Linkers | Uniform PEG cross linkers: Heterobifunctional Amine & Thiol Reactive

Heterobifunctional Amine and Thiol Reactive Uniform PEG Cross-Linkers are polyethylene glycol (PEG)-based molecules engineered with two distinct reactive groups—typically an NHS ester for amine conjugation and a maleimide or similar moiety for thiol conjugation.

This configuration enables the site-specific and stable cross-linking of biomolecules containing primary amines (e.g., lysine residues) and sulfhydryl groups (e.g., cysteine residues).

The uniform PEG backbone provides solubility, biocompatibility, and spatial flexibility, making these cross-linkers ideal for applications in protein engineering, drug delivery, and bioconjugation.