SpeakEasy Science Blog

The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.

The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.

This blog post covers how glycans and t-cells are connected and their importance in the immune system response.

This blog post covers how glycans contribute to cellular mechanisms of health and disease.

This blog post covers how glycans are being used in new frontiers, such as biomarker discovery for cancer and other research fields.

This blog post covers lectin diversity and where lectins come from.

This blog post provides information on the classification, characterization, and applications of glycan-binding proteins.