Ricin A chain has been isolated from toxic RCA II. Our ricin A chain has less than 0.01% of the toxicity of the native lectin in a cell culture test system, yet is as potent as native ricin in a cell-free protein synthesis assay. The A chain can be linked to other proteins such as antibodies. These antibody-hybrid molecules can be used to kill specific cells with the appropriate antigenic determinant exposed, such as tumor markers on surfaces of malignant cells. The A chain is supplied in buffered saline with sodium azide as a preservative.
| Unit Size | 0.5 mg |
|---|---|
| Applications | Cellular toxicity |
| Recommended Storage | 2-8 °C |
| Solution | 10 mM phosphate, 0.15 M NaCl, pH 7.5, 0.08% sodium azide, 50 mM 2-mercaptoethanol, 0.1% polyethylene glycol (M.W. 3300) |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
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