Propargyl amine

Propargyl amine, product number QBD-10510, is an amine-functionalized, three-carbon, terminal aliphatic alkyne. A non-dPEG® product, propargyl amine (formally, prop-2-yn-1-amine) is an alkynyl partner for Quanta BioDesign’s azide-functionalized dPEG®-based click chemistry reagents. Click chemistry using propargyl amine and azides requires catalysis. Copper(I) catalysis leads to the 1,3-dipolar cycloaddition product. Ruthenium catalysis forms the 1,5-dipolar cycloaddition product. The terminal amine can be reacted with any of Quanta BioDesign’s dPEG® NHS or TFP esters or carboxylic acid products to form any desired product.

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SKU: QBD-10510
CAS Number
2450-71-7
Molecular Weight
55.08; single compound
Chemical Formula
C₃H₅N
Purity
> 98%
Unit Size
1000 mg
Solubility
Methylene chloride, Acetonitrile, DMAC or DMSO.
Spacers
Spacer is 4 atoms and 3.5 Å
Storage Instructions
-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.
Shipping Instructions
Ambient