Propargyl-Maleimide enables simple and efficient incorporation of terminal alkyne group onto antibodies, cysteine-containing peptides or other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. A short spacer arm adds minimal mass to modified molecules (130.1 daltons).
|Unit Size||25 mg, 100 mg, 1000 mg|
|Chemical composition||C 7H5NO2|
|Solubility||DMSO, DMF, DCM, THF, Chloroform|
|Appearance||Slightly grey to slightly orange solid|
|Storage Conditions||-20°C. Desiccate|
|Shipping Conditions||Ambient temperature|
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