N-(4-pentynoyl)-glucosamine tetraacylated (Ac4GlcNAl) (CCT-1155)


Ac4GlcNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.


Unit Size5 mg, 25 mg, 100 mg
Molecular weight427.40
Chemical compositionC19H25NO10
SolubilityDMSO, DMF, DCM, THF, Chloroform
AppearanceWhite to grey amorphous solid
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Selected References

  1. Wood, T. M., et al. (2021). Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS Chem. Biol., [PubMed]

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