AZDye 680 Picolyl Azide

AZDye™ 680 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported (see Selected References).

Price range: $215.00 through $4,097.00

Category: AZ Dyes

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SKU: CCT-1511

CAS Number N/A
Molecular Weight 1030.63 (protonated)
Appearance Blue solid
Extinction Coefficient 185,000
Purity >90% (HPLC)
Unit Size 1 mg, 5 mg, 25 mg, 100 mg
Solubility Water, DMSO, DMF
Storage Instructions -20°C. Desiccate
Spectrally Similar Dyes Alexa Fluor® 680, IRDye® 680RD, CF™ 680 Dye
Laser Line 633 nm or 647 nm
Excitation/Emission Maximum 678/701 nm
Shipping Conditions Ambient temperature
Shipping Instructions Ambient temperature

Abs/Em Spectra

Cy5.5

Selected References

Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem.,, 25, 698-706. [PubMed]
Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,., 51, 5852-56. [PubMed]
Gaebler, A.,et al. (2016). A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins. J. Lipid. Res., 57, 1934-47. [PubMed]