Amino-dPEG®₂-t-butyl ester

Amino-dPEG®2–t-butyl ester, product number QBD-10264, is a monodispersed polyethylene glycol (PEG) crosslinker containing a primary amino group and a tert-butyl ester-protected propionic acid group. The terminal amine reacts with carboxylates to form amide bonds and with aldehydes and ketones to form semi-labile, reducible Schiff bases. The tert-butyl ester protecting group removes easily with trifluoroacetic acid (TFA), leaving the propionic acid free to react with amines or form an active ester with N-hydroxysuccinimide (NHS) or 2,3,5,6-tetrafluorophenol (TFP). This compound is useful as a building block in supramolecular construction, a peptide modification reagent, a surface coating for biomolecules and inorganic/metal surfaces, or for protein modification.

Price range: $109.00 through $158.00

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SKU: QBD-10264
CAS Number
756525-95-8
Molecular Weight
233.30; single compound
Chemical Formula
C₁₁H₂₃NO₄
Purity
> 98%
Unit Size
100 mg, 1000 mg
Solubility
Methylene chloride, DMAC, or DMSO.
Spacers
dPEG® Spacer is 10 atoms and 10.9 Å
Storage Instructions
-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.
Shipping Instructions
Ambient