Alkyne-PEG4-Acid (CCT-TA102)

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Description

Alkyne-PEG4-Acid is a polyethylene glycol-containing reagent with a terminal carboxylic acid (–COOH) that can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) forming a stable amide bond. The terminal alkyne group reacts with azides by a mechanism known as the Cu-catalyzed click reaction enabling efficient and specific conjugation of derivatized molecules in biological samples.

Specifications

Unit Size100 mg, 1000 mg
Molecular weight304.34
Chemical compositionC14H24O7
CAS1245823-51-1
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (HPLC)
AppearanceColorless to slightly yellow oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Selected References

  1. Graham, A. J., et al. (2022). Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition. ACS Cent Sci.8 (2), 246-257. [PubMed]

Applicable patents and legal notices are available at legal notices.

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