Boc Protected Aminooxy Reagents

Payload Delivery Linkers and Modifiers | Multifunctional Uniform PEG Linkers: Boc Protected Aminooxy Reagents

Boc-Protected Aminooxy Reagents in multifunctional uniform PEG linkers are PEG-based molecules featuring an aminooxy (-ONH₂) group that is temporarily protected with a Boc (tert-butyloxycarbonyl) group.

The Boc protection prevents premature reactivity, allowing for selective deprotection and subsequent conjugation with aldehyde or ketone groups via stable oxime bond formation. These reagents are ideal for controlled bioconjugation workflows, enabling site-specific labeling or drug attachment while leveraging the solubility, flexibility, and biocompatibility of PEG.