Antibodies and Reagents for Infectious Disease Research
The Vector Laboratories portfolio now includes a synergistic collection of antibody-centric brands — Absolute Antibody, LSBio, Everest Biotech, Exalpha, Nordic-MUbio, and Kerafast.
The rapid evolution of pathogens that cause infectious diseases poses a risk to not only public health, but also agriculture and commerce. Within the past decade, society has witnessed the proliferation and global spread of new and resurged illnesses and the devastation they can impose. Research into disease causing pathogens remains a necessity. Vector Laboratories is committed to providing researchers with an extensive portfolio of high-quality reagents for immunohistochemistry (IHC) and immunofluorescence (IF), including primary antibodies against viral, bacterial, and other pathogenic targets, to help further infectious disease studies.
Antibodies for Virus Research
In virology research, the pursuit of groundbreaking discoveries hinges on the precision and reliability of research tools. High-quality reagents play a pivotal role in unraveling the intricacies of viral biology, aiding scientists in virus identification, pathway and neutralization studies, and vaccine development. The need for antibodies with exceptional specificity and sensitivity is paramount to accurately discern virus-host interactions. Our extensive catalog of research products empowers virology researchers by providing tools that meet the demands of today’s scientific inquiries.
Featured Anti-Virus Antibodies for Immunofluorescence and Immunohistochemistry
Double-Stranded RNA Antibodies
Double-stranded RNA (dsRNA) can constitute the genome of some viruses (dsRNA viruses) or be generated in host cells during viral replication. These qualities play a pivotal role in the ability of researchers to identify viral infections and study infectious disease.
SCICONS™
SCICONS mouse anti-dsRNA antibodies are a highly cited offering used for the detection of dsRNA in immunofluorescence applications. These antibodies have been widely applied to study the viral life cycle and anti-viral responses, as well as used as a diagnostic tool to detect whether an unknown pathogen is bacterial or viral.
SCICONS™
[9D5]: This recombinant dsRNA antibody does not react to ssRNA, ribosome RNA, tRNA and DNA, and is available in a variety of species-swapped, engineered versions to suit immunofluorescence and other applications.
Additionally, Vector Laboratories provides antibodies against Vesicular Stomatitis Virus and Flavivirus that have been trusted in numerous cited applications.
Popular Virus Research Areas
Vector Laboratories’ extensive catalog of research products includes antibodies to common virology targets, including COVID-19, RSV, Mpox, and H5N1. We offer recombinant antibodies, polyclonal antibodies, proteins, detection kits, and laboratory manufactured reagents to enable virology research.
COVID-19
Recombinant Antibodies
Detection Kits, Antibodies and Proteins
Exclusive Institution-Derived Antibodies
RSV
Recombinant Antibodies
Antibodies and Proteins
Bird Flu (H5N1)
Recombinant Antibodies
Antibodies and Proteins
Mpox
Recombinant Antibodies
Antibodies for Bacteria Research
Bacteria are sturdy organisms that can be found nearly everywhere and can survive in even the most extreme environments. Most of these microbes are benign, however, there are species of bacteria that can be pathogenic and cause illness in humans and animals. Vector Laboratories offers a variety of products for use in bacterial studies including antibodies to top priority pathogens for antimicrobial resistance research.
Featured Anti-Bacteria Antibodies for Immunofluorescence
Popular off-the-shelf antibodies are available for various bacterial targets, including Mycobacterium and Borrelia. These recombinant antibodies can be customized into different species, isotypes, and formats to suit research and application requirements.
| Bacteria | Molecule | Catalog # | Antibody Type | Species | Application(s) | Link |
|---|---|---|---|---|---|---|
| Mycobacterium spp. | Lipoarabinomannan (LAM) | Ab02211 | Recombinant | Rabbit, Mouse | IF | View |
| Mannose-capped lipoarabinomannan (ManLAM) | Ab03325 | Recombinant | Human, Mouse, Rabbit | IF | View | |
| Borrelia spp. | Outer surface protein A (OspA) | Ab01070 | Recombinant | Dog, Human, Mouse, Rabbit | IF | View |
| Outer surface protein B (OspB) | Ab03011 | Recombinant | Dog, Human, Mouse, Rabbit | IF | View | |
| Flagellar antigen | Ab04317 | Recombinant | Human, Mouse, Rabbit | IF | View |
Antimicrobial Resistance
Antimicrobial resistant bacteria continue to emerge as a global threat, necessitating public and private institutions to invest in non-traditional antibacterials, such as antibodies, to combat these microscopic pathogens. Vector Laboratories’ expansive catalog includes antibodies and proteins that can be utilized for AMR research. Additionally, our recombinant antibody services can provide solutions to researchers studying antimicrobial resistant bacteria. Learn more about the benefits of recombinant antibody technology for the development of antimicrobial solutions in Absolute Antibody’s blog post.
IHC-Validated Antibodies
Our LSBio brand specializes in IHC validation, offering more than 15,000 antibodies validated for immunohistochemistry with a focus on cancer biomarkers.
IHC-Plus™ antibodies have been rigorously tested to deliver optimal performance in immunohistochemistry (IHC) studies on formalin-fixed paraffin-embedded (FFPE) human tissues.
PathPlus™ antibodies represent the highest quality reagents available for research pathology applications, shown to be the best performing reagents for immunohistochemical detection of high-value cancer targets.
Goat Polyclonal Antibodies
Our Everest brand specializes in anti-peptide and antigen affinity purified goat polyclonal antibodies, especially useful in applications that require high affinity antibodies at cost-effective prices.
The catalog contains thousands of goat antibodies against a broad range of human, mouse, and rat proteins of biomedical interest, like IGF1, FOXP3/SCURFIN, and CEP290. Many of Everest’s antibodies include validation data in ELISA and western blot (WB) applications.
Featured Primary Antibodies
These highly-cited antibodies from the Vector portfolio target antigens of interest in cancer research.
Anti-Laminin Rat Antibody (MUB1100P)
Immunofluorescence staining of frozen sections from human colon (methanol fixed) using MUB1100P, showing the localization of laminin, a protein that plays a role in tumorigenesis and metastasis in a variety of cancer types.
Featured Cancer Research Areas
Our high-quality antibodies and reagents support cancer research across multiple applications, enabling the study of key biomarkers and pathways in breast, colorectal, lung, and prostate cancer. Explore how our products advance research in these featured cancer types.
Breast Cancer
Labeling specific markers is crucial for breast cancer research, from tumor characterization to therapy selection and mechanistic studies. Standard markers like HER2, ER, and PR guide treatment, while Ki-67, TP53, and p63 assess proliferation and invasion. Antibody-based tools also support genetic research on BRCA mutations and predictors like SIAH2 and EGFR. Our reagents enable precise biomarker analysis across various applications.
Colorectal Cancer
Colorectal carcinoma (CRC) affects 4% of the population, requiring reliable reagents for diagnostics and therapy development. Antibodies aid in biomarker identification, including CDX2 and Villin, oncogenic mutations in chromosomal instability, and targets for therapies like EGFR and VEGF inhibitors. Our products , advancing CRC research and treatment strategies.
Lung Cancer
Lung cancer remains a leading cause of cancer deaths, with accurate biomarker detection critical for classification and treatment. Tissue-specific markers like TTF-1 and p63 help subtype tumors, while EGFR, ALK, and PD-L1 guide targeted therapies. Frequent mutations in KRAS, BRAF, and TP53 further shape lung cancer progression. Our antibodies support diagnostics, biomarker research, and therapeutic development.
Prostate Cancer
Prostate cancer is the most common non-skin cancer in men, requiring precise biomarker detection for diagnosis and treatment. Antibodies help identify key markers such as PSA, Prostein, NKX3-1, p63, and AMACR while enabling research into AR, WNT, and PI3K pathway alterations. Our reagents support diverse applications, advancing diagnostics and therapeutic development for prostate cancer.
Technical and Educational Cancer Research Resources
For more information on how Vector’s portfolio of products supports cancer research, explore the following resources.
Therapeutic Antibody Mechanisms of Action
Learn more about how antibody therapeutics work for cancer and other diseases, including how antibody format affects treatment efficacy.
IHC-Validated Cancer Research Antibodies from LSBio
These pages provide further information on clinically relevant antibody targets for each cancer type, as well as offering IHC-validated antibody options for each.
IHC-Validated Cancer Research Antibodies from LSBio
These pages provide further information on clinically relevant antibody targets for each cancer type, as well as offering IHC-validated antibody options for each.
Anti-Tumor Efficacy of Syngeneic Engineered Anti-PD-1 vs. Original Antibody
This research poster demonstrates that a recombinant, species-switched version of an anti-PD-1 antibody shows greater therapeutic efficacy in vivo than the original version.
