Maackia Amurensis Lectin II (MAL II), Unconjugated

Although the specificity of this lectin is not well defined, MAL II appears to bind only particular carbohydrate structures that contain sialic acid. Unlike Sambucus nigra lectin (SNA) which seems to prefer structures with (α-2,6) linked sialic acid, MAL II appears to bind sialic acid in an (α-2,3) linkage. Tissue staining patterns are also very different among MAL I, SNA and MAL II.

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SKU: L-1260-2
Molecular Weight
130
Extinction Coefficient
1.33
Formulation
10 mM HEPES, pH 7.5, 0.15 M NaCl, 0.08% sodium azide, 0.1mM CaCl2.
Inhibiting or Eluting Sugar
Neuraminidase treatment or Fetuin
Unit Size
2 mg
Storage Instructions
2-8 °C
Sugar Specificity
α2,3-sialylated Galb1−3GalNAc in O-glycans, and 3′O-sulfated Gal.
Applications
Glycobiology, Mitogenic Stimulation
Concentration
2 mg/ml
Conjugate
Unconjugated
Technical Information
Maackia amurensis lectin II is a glycoprotein consisting of two subunits each of which is composed of disulfide-linked chains.

Geisler, C and Jarvis, D.L. Glycobiology, vol. 21, no. 8 pp. 988-993, 2011

Inhibitor: Human glycophorin