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SY-21 DBCO (FP-1715)

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Description

SY-21 DBCO (QSY®-21 equivalent) is a nonfluorescent acceptor dye often used for preparation of peptide and oligonucleotide FRET probes. A broad and intense quenching range from 580 nm to 680 nm makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 580 nm to 680 nm, such as Fluorescein, Alexa Fluor® 568, 594, 633, 647, TAMRA, ROX, Texas Red and Cy5.

SY-21 DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. In application where the presence of copper is a concern SY-21 DBCO is an ideal alternative to copper requiring fluorescent alkynes.

Specifications

Unit Size5 mg, 25 mg, 100 mg
Reactivity
Azide
Abs/Em Maxima661 nm
Extinction coefficient90,000 cm-1M-1
SolubilityDMSO, DMF
Spectrally similar dyesAlexa Fluor® 568, 594, 633, 647, TAMRA, ROX, Texas Red, Cy5.
Molecular weight1091.27
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Abs/Em Spectra

SY 21 SY-21

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