N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz)

The unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Price range: $149.00 through $691.00

Category: Glycosylation

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SKU: CCT-1086

CAS Number 653600-56-7
Molecular Weight 430.37
Appearance White to grey amorphous solid
Chemical Formula C16H22N4O10
Purity >90%
Unit Size 5 mg, 25 mg, 100 mg
Solubility DMSO, DMF, DCM, THF, Chloroform
Storage Instructions -20°C.
Shipping Conditions Ambient temperature
Shipping Instructions Ambient temperature

Selected References

Simon P. Wisnovsky, et al. (2020). Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation. PNAS, 117 (41), 25293-25301. [PNAS]
Ranzinger, R., et al. (2020). Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. ACS Chem. Biol., 15, 10, 2692-2701. [ACSPublications]
Suttapitugsakul, S., et al. (2019). Surface Glycoproteomic Analysis Reveals That Both Unique and Differential Expression of Surface Glycoproteins Determine the Cell Type. Anal. Chem., 91(10), 6934–42. [PubMed]