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F-ara-EdU (CCT-1403)

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Description

F-ara-EdU is a probe for DNA synthesis that is less toxic compared to 5-ethynyl-2′-deoxyuridine (EdU) and BrdU. Ideally suited for metabolic DNA labeling experiments where long-term cell survival and/or deep-tissue imaging are desired. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction.

Specifications

Unit Size5 mg, 25 mg, 100 mg, 500 mg
Molecular weight270.22
Chemical compositionC11H11NF2O5
CASN/A
SolubilityWater, DMSO, DMF
Purity>95% (HPLC)
AppearanceOff white to grey crystalline
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Selected References

  1. Raz, A. A., et al. (2021). Planarian stem cells specify fate yet retain potency during the cell cycle. Cell Stem Cell.28 (7), 1307-1322.e5. [PubMed]
  2. Neef, A.B., et al. (2011). Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides. PNAS,108, 20404-9. [PubMed]

Applicable patents and legal notices are available at legal notices.

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