Propargyl-Maleimide enables simple and efficient incorporation of terminal alkyne group onto antibodies, cysteine-containing peptides or other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. A short spacer arm adds minimal mass to modified molecules (130.1 daltons).
Unit Size | 25 mg, 100 mg, 1000 mg |
---|---|
Molecular weight | 130.12 |
Chemical composition | C 7H5NO2 |
CAS | 209395-32-4 |
Solubility | DMSO, DMF, DCM, THF, Chloroform |
Purity | >95% (HPLC) |
Appearance | Slightly grey to slightly orange solid |
Storage Conditions | -20°C. Desiccate |
Shipping Conditions | Ambient temperature |
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