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Cy5.5 Alkyne (CCT-1060)

[text-backorder]

This product was previously sold as 1346 from Fluoroprobes.

Description

The NIR-fluorescent Cy5.5 Alkynee can be reacted with azides (Ne) via a copper-catalyzed click reaction (CuAAC) forming a stable triazole and does not require elevated temperatures.

Cy5.5 Alkyne is a bright and photostable near-IR probe that spectrally similar to Alexa Fluor® 680, DyLight® 680, and IRDye® 680 dye. The Cy5.5 Alkyne is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy5.5 is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.

Specifications

Unit Size1 mg, 5 mg, 25 mg, 100 mg
Abs/Em Maxima678/694 nm
Extinction Coefficient
190,000
Spectrally Similar DyesAlexa Fluor® 680, IRDye® 680RD, DyLight® 680
Molecular weight940.09
CASN/A
SolubilityWater, DMSO, DMF
Purity>95% (HPLC)
AppearanceBlue solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Abs/Em Spectra

Cy Cy

Selected References

  1. Willems, L. I., et al. (2020). Tandem Bioorthogonal Labeling Uncovers Endogenous Cotranslationally O-GlcNAc Modified Nascent Proteins. J Am Chem Soc.142 (37), 15729-15739. [PubMed]
 

Applicable patents and legal notices are available at legal notices.

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