Alkynyl Palmitic Acid

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry (see References).

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SKU: CCT-1165
CAS Number
99208-90-9
Molecular Weight
252.39
Appearance
White crystalline
Chemical Formula
C16H28O2
Purity
>95% (H NMR)
Unit Size
5 mg, 25 mg, 100 mg
Solubility
DMSO, DMF, DCM, THF, Chloroform
Storage Instructions
-20°C.
Synonym / Alias Names
15-hexadecynoic acid, Palmitic acid (15-yne)
Shipping Conditions
Ambient temperature
Shipping Instructions
Ambient temperature
Selected References
  1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107. [JoVE Journal]
  2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890. [PubMed]
  3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res . [PubMed]
  4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501. [PubMed]