Alkyne-PEG4-Acid

Alkyne-PEG4-Acid is a polyethylene glycol-containing reagent with a terminal carboxylic acid (–COOH) that can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) forming a stable amide bond. The terminal alkyne group reacts with azides by a mechanism known as the Cu-catalyzed click reaction enabling efficient and specific conjugation of derivatized molecules in biological samples.

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SKU: CCT-TA102
CAS Number
1245823-51-1
Molecular Weight
304.34
Appearance
Colorless to slightly yellow oil
Chemical Formula
C14H24O7
Purity
>95% (HPLC)
Unit Size
100 mg, 1000 mg
Solubility
DMSO, DMF, DCM, THF, Chloroform
Storage Instructions
-20°C. Desiccate
Shipping Conditions
Ambient temperature
Shipping Instructions
Ambient temperature
Selected References
  1. Graham, A. J., et al. (2022). Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition. ACS Cent Sci., 8 (2), 246-257. [PubMed]