Cy3 Alkyne

Cy3 Alkyne can be reacted with azides via a copper-catalyzed click reaction (CuAAC) forming a stable triazole and does not require elevated temperatures. This red fluorescent probe is water-soluble, and its fluorescence is pH-insensitive from pH 4 to pH 10. Its excitation peak is ideally suited for the 532 nm or 555 nm laser lines and its absorption and emission spectra are almost identical to those of Alexa Fluor® 555, CF® 555 Dye or any other Cyanine3 based fluorescent dyes.

Price range: $153.00 through $2,896.00

Category: Cy3 Dyes

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SKU: CCT-TA117

CAS Number N/A
Molecular Weight 964.31
Molecular Formula C47H73N5O10S3
Appearance Red solid
Chemical Formula C47H73N5O10S3
Extinction Coefficient 150,000
Purity >95% (HPLC)
Unit Size 1 mg, 5 mg, 25 mg, 100 mg
Solubility Water, DMSO, DMF
Storage Instructions -20°C. Desiccate
Spectrally Similar Dyes Alexa Fluor® 555, Atto™ 555, CF® 555 Dye, DyLight®549
Laser Line 532, 555 or 568 nm
Excitation/Emission Maximum 549 nm / 562 nm
Shipping Conditions Ambient temperature
Shipping Instructions Ambient temperature

Abs/Em Spectra

Cy3

Selected References

Banerjee, C., et al. (2022). Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET. J Vis Exp., 186. [PubMed]
Schamber, M. R., et al. (2022). Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2. Elife, 11:e78982. [PubMed]
Schamber, M. R., et al. (2022). Mechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning. Nat Commun., 13 (1), 2194. [PubMed]