6-Azide-Trehalose (6-TreAz) (CCT-1472)


Metabolic labeling with unnatural sugar substrates is a powerful alternative for investigating glycoconjugates in living organisms. Trehalose glycolipids can be metabolically labeled with 6-azide-modified trehalose (TreAz) analogues in live mycobacteria, enabling bioorthogonal ligation with alkyne-functionalized fluorescent probes. This strategy can be used for imaging glycolipid distribution, trafficking, and dynamics as well as metabolite profiling and discovery.


Unit Size5 mg, 25 mg, 100 mg
Molecular weight367.31
Chemical compositionC12H21N3O10
SolubilityWater, DMSO, DMF
AppearanceWhite to grey amorphous solid
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Selected References

  1. Swarts, B.M., et al. (2012). Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry.J. Am. Chem. Soc., 134: 13123-6. [PubMed]

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