CAS Number N/A | |
Molecular Weight 691.61; single compound | |
Chemical Formula C₂₆H₅₁BrN₄O₁₂ | |
Purity > 98% | |
Unit Size 100 mg, 1000 mg | |
Solubility Methylene Chloride, DMAC, DMF, and DMSO | |
Spacers dPEG® Spacer is 39 atoms and 46.0 Å | |
Storage Instructions -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure. | |
Shipping Instructions Ambient |
Bromoacetamido-dPEG®₁₁-azide
Bromoacetamido-dPEG®11-azide, product number QBD-11204, crosslinks free thiols with click chemistry alkyne partners across a medium-length (39 atoms, 46.0 Å) single molecular weight, discrete PEG (dPEG®) bridge.
The medium-length dPEG® linker is amphiphilic and adds hydrodynamic volume and water solubility to conjugate molecules. The flexible, non-immunogenic spacer can reduce or eliminate renal clearance and help shield conjugates from opsonization through the increased hydrodynamic volume the dPEG® linker imparts.
The bromoacetate moiety reacts chemoselectively with free thiols at pH >8.0. The bromoacetate group is an alternative to the maleimide group and is used in situations where the target molecule needs to be at a high pH. The azide group reacts with a suitable alkyne partner via metal-catalyzed (Cu, Ru) or strain-promoted (copper-free) click chemistry. Moreover, Bromoacetamido-dPEG®11-azide is stable, unlike MAL-PEG-azide constructs, which are somewhat unstable.
Price range: $383.00 through $1,475.00
| SKU | Unit Size | Price |
|---|---|---|
Select a unit size:
How do I request a quote or bulk pricing?
Documents |
