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DNP-dPEG®₁₂-NHS ester (QBD-10399)



DNP-dPEG®12-NHS ester, product number QBD-10399, is a medium-length (40 atoms), single molecular weight, discrete polyethylene glycol (dPEG®) linker functionalized on one end with the fluorescent hapten 2,4-dinitrophenol and the N-hydroxysuccinimidyl (NHS) ester of propionic acid on the other end. The NHS ester reacts with free amines to form stable amide bonds. The DNP end of the molecule may be used as a hapten in the development of vaccines or immunotherapeutic applications.


Unit Size100 mg, 1000 mg
Molecular Weight880.89; single compound
Chemical formulaC₃₇H₆₀N₄O₂₀
Purity> 98%
SpacersdPEG® Spacer is 40 atoms and 46.4 Å
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.


Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Applicable patents and legal notices are available at legal notices.

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