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5-TAMRA Cadaverine (FP-1261)

This product was previously sold as 1248 from Click Chemistry Tools.

Description

Vectorlabs

5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).

Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.

Specifications

Unit Size5 mg, 25 mg, 100 mg, 1000 mg
ReactivityPrimary amines
Abs/Em Maxima553/575 nm
Extinction coefficient91,000 cm-1M-1
SolubilityDMSO, DMF, MeOH
Spectrally similar dyesAlexa Fluor® 546, TAMRA, CF™ 543, MB™ 543
Molecular weight627.24 (TFA salt)
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Abs/Em Spectra

Tamra Tamra Vectorlabs

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