Vector Laboratories is closed for the President’s Day on Monday, February 19th. We will be back in the office on Tuesday, February 20th.
We will respond to emails upon our return. Have a wonderful day.

TCO-PEG4-NHS Ester (CCT-A137)



TCO-PEG4-NHS Ester is a pegylated lebeling reagent with enhanced solubility in aqueous buffers used for TCO labeling of antibodies, proteins and other primary amine-containing macromolecules. A long, hydrophilic PEG4 spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.


Unit Size4x2mg, 10mg, 25mg, 100mg
Molecular weight514.57
Chemical compositionC24H38N2O10
SolubilityDMSO, DMF, THF, Acetonitrile, Dichloromethane
Purity>95% (HPLC)
AppearanceColorless to slightly yellow oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsDry ice

Selected References

  1. Ingham, E. S., et al. (2020). Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun, 11, 2102. [Nature Communications]
  2. Sun, N., et al. (2020). Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring. Nat Commun.11, 4489. [PubMed]
  3. Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. 29(6), 2028-38. [PubMed]

Applicable patents and legal notices are available at legal notices.

How do I Request a Quote?

To request a quote for products:

  1.  Log in to
  2.  Add the items you wish to quote to the cart;
  3.  View your cart;
  4.  Click on the “Request a Quote” button found below the items in your cart;
  5.  Download your quote