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m-dPEG®₁₃-DSPE (QBD-10052)

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Description

m-dPEG®13-DSPE, product number QBD-10052, is composed of the lipid 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), modified with a methoxy-terminated, single molecular weight, discrete polyethylene glycol (dPEG®). The medium-length (41 atoms, 47.1 Å) dPEG® spacer protects liposomes and micelles from opsonization and elimination by the reticuloendothelial system (RES).

Specifications

Unit Size 25 mg, 100 mg
Molecular Weight 1362.79; single compound
Chemical formula C₆₉H₁₃₆NO₂₂P
CAS
N/A
Purity > 98%
Spacers
dPEG® spacer is 41 atoms and 47.1 Å.
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support) DCM, Ethyl acetate, Acetonitrile, Methanol, or MTBE
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

References

  1. Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

  2. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

Applicable patents and legal notices are available at legal notices.

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