m-dPEG®13-DSPE, product number QBD-10052, is composed of the lipid 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), modified with a methoxy-terminated, single molecular weight, discrete polyethylene glycol (dPEG®). The medium-length (41 atoms, 47.1 Å) dPEG® spacer protects liposomes and micelles from opsonization and elimination by the reticuloendothelial system (RES).
| Unit Size | 25 mg, 100 mg |
|---|---|
| Molecular Weight | 1362.79; single compound |
| Chemical formula | C₆₉H₁₃₆NO₂₂P |
| CAS |
N/A
|
| Purity | > 98% |
| Spacers |
dPEG® spacer is 41 atoms and 47.1 Å. |
| Shipping |
Ambient |
| Typical solubility properties (for additional information contact Customer Support) | DCM, Ethyl acetate, Acetonitrile, Methanol, or MTBE |
| Storage and handling | -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure. |
Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.
Applicable patents and legal notices are available at legal notices.
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