CAS Number N/A | |
Molecular Weight 1067.12; single compound | |
Chemical Formula C₅₃H₇₀F₄N₂O₁₆ | |
Purity > 98% | |
Unit Size 25 mg, 100 mg, 500 mg | |
Solubility Methylene Chloride, DMSO, DMAC, Methanol, DMF, or Acetonitrile. | |
Spacers dPEG® Spacer is 40 atoms and 46.3 Å | |
Storage Instructions -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure. | |
Shipping Instructions Ambient |
DBCO-dPEG®₁₂-TFP ester
DBCO-dPEG®12-TFP ester, product number QBD-11366, is a heterobifunctional, bioorthogonal crosslinker designed to join azides and amines across a medium-length (40 atoms, 46.3 Å), flexible, hydrophilic, single molecular weight, discrete PEG (dPEG®) spacer. The tetrafluorophenyl (TFP) ester reacts specifically with free amines to form amide bonds; the optimum reaction pH is 7.5 – 8.0. The dibenzylcyclooctyne (DBCO) moiety selectively forms triazole linkages with azides via a click chemistry reaction known as strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. The amphiphilic dPEG® linker increases conjugates’ hydrodynamic volumes, and it can be used to create space in sterically crowded supramolecular constructs.
Price range: $213.00 through $1,913.00
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