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Unconjugated Vicia Villosa Lectin (VVL, VVA)

Catalog Number: L-1230

Availability: In stock

$130.00
Unit Size: 5 mg

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Overview

    VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.

    Additional Information

    Catalog Number L-1230
    Unit Size 5 mg
    Country of Manufacture United States
    Applications Glycobiology
    Conjugate Unconjugated
    Sugar Specificity N-Acetylgalactosamine
Additional Info

    Details

    This lectin is a family of tetrameric glycoproteins consisting of combinations of A and B subunits similar in structure to PHA and GSL I. The dominant isolectins in our preparations appear to be B subunit-rich. VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.

    Inhibiting/Eluting Sugar: 200 mM N-acetylgalactosamine
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    You're reviewing: Unconjugated Vicia Villosa Lectin (VVL, VVA)

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