Unconjugated Vicia Villosa Lectin (VVL, VVA)

Cat. No: L-1230
Price: $142.00
Unit Size: 5 mg

Overview

VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.

Cat. No. L-1230-5
Unit Size 5 mg
Country of Manufacture United States
Applications Glycobiology
Conjugate Unconjugated
Sugar Specificity N-Acetylgalactosamine

More Information

This lectin is a family of tetrameric glycoproteins consisting of combinations of A and B subunits similar in structure to PHA and GSL I. The dominant isolectins in our preparations appear to be B subunit-rich. VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.

Inhibiting/Eluting Sugar: 200 mM N-acetylgalactosamine

Protocols/Data Sheets/SDS