Ricinus Communis Agglutinin II (RCA II, RCA60, ricin), Unconjugated


This product has been discontinued.

We have discontinued this product permanently. Please find alternative products from below section.
SKU Unit Size Price
L-1090-10 10 mg

To request a quote for products:

  1. Click “Contact Us” in the header bar above;
  2. Click “Customer Service”;
  3. Complete the form and provide the following information in the “Comments” section: note you would like a quote, item number (SKU) and quantity;
  4. Click “Submit”.


TOXIC! This product is not available for purchase online. Please call Vector Laboratories for ordering information. 

Ricinus communis agglutinin II is an extremely toxic glycoprotein consisting of two disulfide-linked chains of about 28 kDa and 32 kDa, termed A and B chain, respectively. The B chain can bind to cell surfaces via galactose or N-acetylgalactosamine residues of membrane glycoconjugates and facilitates the transport of the lectin into the cell. The A chain has an enzyme activity which can catalytically block protein synthesis and is so toxic that only a single molecule of A chain is required to kill a cell. Alone, the A chain is incapable of entering the cell and is thus not toxic.

RCA II appears to be a family of related lectins with different toxicities. Our RCA II is the most toxic lectin of this family, probably ricin D, having an I.P. L.D50 in 20 g mice of less than 50 ng.


More Information
Unit Size 10 mg
Applications Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Glycobiology
Recommended Storage 2-8 °C
Solution 10 mM sodium phosphate, 0.15 M NaCl, pH 7.8, 0.08% sodium azide, 5 mM galactose
Concentration 5.0 mg/ml
Conjugate Unconjugated
Sugar Specificity Galactose, N-Acetylgalactosamine, Lactose


Technical Information

Inhibiting/Eluting Sugar: 200 mM galactose or lactose

Please note: Due to the toxicity of this product, special packaging is required and there is an additional shipping charge, sold in USA only.