Unconjugated Narcissus Pseudonarcissus (Daffodil) Lectin (NPL, NPA)

Cat. No: L-1370
Price: $147.00
Unit Size: 5 mg

Overview

NPL, isolated from daffodil bulbs, has a specificity toward α-linked mannose, preferring polymannose structures containing (α-1,6) linkages. Binding to mannose polymers can occur via internal mannose residues and is not dependent on structural integrity of a non-reducing end sugar. NPL also binds some galactomannans, and differs in other binding characteristics from a related lectin, Galanthus nivalis lectin. Unlike Con A, LCA, or PSA, NPL does not bind glucose.

Cat. No. L-1370-5
Unit Size 5 mg
Country of Manufacture United States
Applications Glycobiology
Conjugate Unconjugated
Sugar Specificity Mannose

More Information

This lectin exists as a tetramer at neutral pH but below pH 5.0 and above pH 9.0, NPL dissociates into monomers. NPL, isolated from daffodil bulbs, has a specificity toward α-linked mannose, preferring polymannose structures containing (α-1,6) linkages. Binding to mannose polymers can occur via internal mannose residues and is not dependent on structural integrity of a non-reducing end sugar. NPL also binds some galactomannans, and differs in other binding characteristics from a related lectin, Galanthus nivalis lectin. Unlike Con A, LCA, or PSA, NPL does not bind glucose.

Inhibiting Sugar: 400 mM α-methylmannoside

Protocols/Data Sheets/SDS