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Unconjugated Narcissus Pseudonarcissus (Daffodil) Lectin (NPL, NPA)

Catalog Number: L-1370

Availability: In stock

$135.00
Unit Size: 5 mg

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Overview

    NPL, isolated from daffodil bulbs, has a specificity toward α-linked mannose, preferring polymannose structures containing (α-1,6) linkages. Binding to mannose polymers can occur via internal mannose residues and is not dependent on structural integrity of a non-reducing end sugar. NPL also binds some galactomannans, and differs in other binding characteristics from a related lectin, Galanthus nivalis lectin. Unlike Con A, LCA, or PSA, NPL does not bind glucose.

    Additional Information

    Catalog Number L-1370
    Unit Size 5 mg
    Country of Manufacture United States
    Applications Glycobiology
    Conjugate Unconjugated
    Sugar Specificity Mannose
Additional Info

    Details

    This lectin exists as a tetramer at neutral pH but below pH 5.0 and above pH 9.0, NPL dissociates into monomers. NPL, isolated from daffodil bulbs, has a specificity toward α-linked mannose, preferring polymannose structures containing (α-1,6) linkages. Binding to mannose polymers can occur via internal mannose residues and is not dependent on structural integrity of a non-reducing end sugar. NPL also binds some galactomannans, and differs in other binding characteristics from a related lectin, Galanthus nivalis lectin. Unlike Con A, LCA, or PSA, NPL does not bind glucose.

    Inhibiting Sugar: 400 mM α-methylmannoside
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