Musa Paradisiaca (Banana) Lectin (BanLec), Unconjugated

L-1410
SKU Unit Size Price Qty
L-1410-5 5 mg
$124.00

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Description

Isolated from the cultivated banana Musa paradisiaca, banana lectin (BanLec) is a very stable mannose- and glucose-binding lectin consisting of two identical 15 kDa subunits and a reported isoelectric point of pH 7.3. Although structurally related to the Jacalin family of lectins, BanLec recognizes internal α(1,3) glucosyl- and mannosyl- residues and has also been reported to bind β(1,3) and β(1,6) glucosyl-structures.

Like Galanthus nivalis lectin, BanLec has been shown to bind gp 120 glycoprotein, an important envelope component of the human immunodeficiency virus (HIV-1), and to strongly inhibit HIV-1 entry into cells. Glycoproteins on the surface of other viruses are also likely to be recognizable by BanLec. This lectin has been reported to be a potent mitogen for peripheral T-cells in the presence of interleukin-2, and appears likely to be a cause of allergic reaction to bananas, since IgG4 antibodies against BanLec have been detected in humans.

Specifications

More Information
Unit Size 5 mg
Applications Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Glycobiology, Mitogenic Stimulation
Recommended Usage Reconstitute lectin with 10 mM HEPES buffered saline, pH 7.5, 0.08% sodium azide.Subsequent storage should be at 4 ºC.
Recommended Storage 2-8 °C
Inhibiting and/or Eluting Sugar 200 mM α-methylmannoside
Conjugate Unconjugated
Sugar Specificity Mannose, Glucose

Documents

Technical Information

Inhibiting/eluting sugar: 200 mM α-methyl mannoside or mannose