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Unconjugated Jacalin

Catalog Number: L-1150

Availability: In stock

Product Name Unit Size Price Qty
Unconjugated Jacalin 25 mg
$225.00

Small intestine:  Jacalin (brown, Vector DAB), Vector Hematoxylin counterstain. Zoom

Overview

    This lectin appears to bind only O-glycosidically linked oligosaccharides, preferring the structure galactosyl (β-1,3) N-acetylgalactosamine. This structure (the T-antigen) is the oligosaccharide to which peanut agglutinin (PNA) binds. However, unlike PNA, Jacalin will bind a mono- or disialylated form of this structure. This lectin has been used to purify human IgA. The specificity of this lectin also affords the opportunity to localize or isolate glycoproteins with O-glycosidically linked oligosaccharide side chains.

    Additional Information

    Catalog Number L-1150
    Unit Size 10 mg, 25 mg
    Country of Manufacture United States
    Applications Glycobiology, Mitogenic Stimulation
    Conjugate Unconjugated
    Sugar Specificity Galactose
Additional Info

    Details

    Jacalin is a lectin composed of four subunits of approximately 16 kDa each. This lectin appears to bind only O-glycosidically linked oligosaccharides, preferring the structure galactosyl (β-1,3) N-acetylgalactosamine. This structure (the T-antigen) is the oligosaccharide to which peanut agglutinin (PNA) binds. However, unlike PNA, Jacalin will bind a mono- or disialylated form of this structure. This lectin has been used to purify human IgA. The specificity of this lectin also affords the opportunity to localize or isolate glycoproteins with O-glycosidically linked oligosaccharide side chains.

    Inhibiting/Eluting Sugar: 800 mM galactose or 100 mM melibiose
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